Research profile · Ancillaries
Tropisetron
5-HT3 receptor antagonist
Available as: 1000mg
Overview
An indole-based serotonin 5-HT3 receptor antagonist approved in many countries as an antiemetic.
Mechanism
Blocks 5-HT3 receptors in the gut and brainstem; it is also a partial agonist at α7 nicotinic acetylcholine receptors.
Research highlights
- Clinical use against chemotherapy-induced nausea and vomiting.
- Studied for cognitive and anti-inflammatory effects through α7 nicotinic receptors.
Compound data
- Type
- Small molecule