Research profile · Secretagogues & IGF-1
AOD9604
Modified hGH fragment (Tyr-hGH 177-191)
Available as: 5mg
Overview
A 16-amino-acid peptide based on the C-terminal region of human growth hormone, developed to study GH effects on fat metabolism separately from its growth-promoting effects.
Mechanism
Stimulates lipolysis and inhibits lipogenesis in animal models. It does not bind the GH receptor or raise IGF-1.
Research highlights
- Reduced body fat in obese rodent models.
- Human obesity trials did not show significant weight loss versus placebo, and development for obesity was stopped.
- Investigated in animal models of cartilage repair.
Compound data
- Length
- 16 amino acids